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Şubat, 2023 tarihine ait yayınlar gösteriliyor

Will future computers run on human brain cells?

A 'biocomputer' powered by human brain cells could be developed within our lifetime, according to researchers who expect such technology to exponentially expand the capabilities of modern computing and create novel fields of study. http://dlvr.it/Sk8h0T

Drug alleviates autism-associated behavior in mice

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. If it is genetically switched off in human nerve cells or in mice, the functional changes and symptoms typical of autism occur. A drug that blocks sodium channels in the cell membrane can reverse the consequences of MYT1L failure and alleviate the functional and behavioral abnormalities in mice. http://dlvr.it/Sk8KGB

Promising treatment for Alzheimer's disease

Researchers have developed small abiotic and drugable cyclic peptides that have proven effective in animal models in diagnosing early pre-symptomatic stage of Alzheimer's and treating the disease by targeting oligomers. When these molecules were combined in a test tube with the small protein amyloid beta, the generation of oligomers was completely blocked, and no subsequent aggregation occurred. http://dlvr.it/Sk7t5m

New hydrogel stem cell treatment repairs injured brain tissue in mice

A new hybrid hydrogel that safely delivers stem cells to brain injury sites in mice has been developed. This solves a major challenge -- keeping stem cells alive for long enough to evolve into the cells required to create new tissue after insertion into a damaged part of the body. http://dlvr.it/Sk7Nlt

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

A new brain connection can explain how early-life stress and adversity trigger disrupted operation of the brain's reward circuit, offering a new therapeutic target for treating mental illness. Impaired function of this circuit is thought to underlie several major disorders, such as depression, substance abuse and excessive risk-taking. http://dlvr.it/Sk6BP4

Reducing social media use significantly improves body image in teens, young adults

Teens and young adults who reduced their social media use by 50% for just a few weeks saw significant improvement in how they felt about both their weight and their overall appearance compared with peers who maintained consistent levels of social media use, according to new research. http://dlvr.it/Sk5Lg5

Healing the brain: Hydrogels enable neuronal tissue growth

Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction. http://dlvr.it/Sk34j4

Head injuries could be a risk factor for developing brain cancer

Previous studies have suggested a possible link between head injury and increased rates of brain tumors but evidence has been limited and often inconclusive. A team has now identified a possible mechanism to explain this link, implicating genetic mutations acting in concert with brain tissue inflammation to change the behavior of cells, making them more likely to become cancerous. Although this study was largely carried out in mice, it suggests that it would be important to explore the relevance of these findings to human gliomas. http://dlvr.it/Sk2cLL

Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder

A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD. http://dlvr.it/SjynNr

Leptin helps hungry mice choose sex over food

To eat or to mate -- that is the question (and the answer is: moderately hungry mice choose to mate). Researchers show that hungry mice prioritize interacting with members of the opposite sex over eating and drinking when their brains are stimulated with leptin, an appetite-suppressing hormone. http://dlvr.it/SjyXHs

Trained brains rapidly suppress visual distractions

Researchers show that while strong distractions may automatically capture our attention, the trained brain can rapidly suppress such distractions to help us efficiently reach our goals. http://dlvr.it/Sjv6vy

Paying attention to faces may be linked with psychopathology levels and 'Big Five' personality traits

A person's personality and psychopathology levels may be associated with how strongly they prefer to focus on human faces within images, according to a new study. http://dlvr.it/Sjnbqs

The drug fasudil is found to reverse key symptoms of schizophrenia in mice

Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia. http://dlvr.it/Sjk0Jk

Space travel influences the way the brain works

Scientists have found how the human brain changes and adapts to weightlessness, after being in space for 6 months. Some of the changes turned out to be lasting -- even after 8 months back on Earth. http://dlvr.it/Sjc5WN

The centrosome plays an important role in neuron migration

Researchers have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. http://dlvr.it/Sjb7B2

Psychostimulants: Cause of differences in duration and intensity of effect explored

Psychostimulants interacting with the dopamine transporter are found in the therapy of neuro-psychiatric disorders, such as ADHD or depression, as well as on the illicit drug market. In order to better understand their exact mode of action and undesirable effects, a research team has been working on the question of why different substances in this group of substances have different effects: According to their results the answer lies in the respective binding time of the substances to the dopamine transporter. This study has just been published in the journal Proceedings of the National Academy of Sciences (PNAS). http://dlvr.it/SjWqYV

Social isolation triggers astrocyte-mediated deficits in learning and memory

In animal models, social isolation triggers memory and learning deficits that are mediated by hyperactivity of the most abundant brain cell, the astrocyte. Importantly, inhibiting this hyperactivity reversed the cognitive deficits associated with social deprivation. http://dlvr.it/SjV8PX

Low brain pressure could be a risk factor for developing glaucoma

Scientists provide additional evidence that intracranial pressure plays an important role in normal-tension glaucoma, which accounts for up to 50 per cent of all glaucoma cases. A recent clinical study demonstrates that low intracranial pressure correlates with impaired patient visibility, especially in the nasal zone. http://dlvr.it/SjNdR0

Fructose could drive Alzheimer's disease

An ancient human foraging instinct, fueled by fructose production in the brain, may hold clues to the development and possible treatment of Alzheimer's disease (AD). http://dlvr.it/SjMTfb

Children use the same brain network as adults for tough problems

Children as young as 4 years old show evidence of a network in the brain found in adults that tackles difficult cognitive problems, a new study found. http://dlvr.it/SjM3s1

Disrupted flow of brain fluid may underlie neurodevelopmental disorders

Researchers have discovered, in rodents, that fluid that circulates through the brain flows to areas critical for normal brain development and function, suggesting that disruptions to its circulation may play an under-recognized role in neurodevelopmental disorders. http://dlvr.it/SjFBZ2

Mushrooms magnify memory by boosting nerve growth

Researchers have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory. http://dlvr.it/SjDtCH

How the 'construction site' of long term memory gets built in the brain

The proteins responsible for forming memories in neurons change depending on experience, a hint at how our brains build memory. http://dlvr.it/Sj7TTQ

Racial disparities in childhood adversity linked to brain structural differences in U.S. children

A new study used MRI and survey data to identify structural differences in regions of the brain linked to threat processing in 9- and 10-year-olds that the researchers linked to disparities in childhood adversity exposure as a result of structural racism. http://dlvr.it/Sj5Vpn

Brain structural differences observed in children with conduct disorder with and without childhood maltreatment

Characterized by antisocial behaviors and low academic achievement, conduct disorder (CD) impacts an estimated 9.5% of individuals in the United States. Childhood maltreatment is a major risk factor for CD. Past CD studies have identified structural alterations in various brain regions, such as those implicated in emotion processing, learning, and social cognition. A new study has now assessed whether youths with CD who experienced childhood maltreatment differ at the brain level from those with CD without a history of maltreatment. http://dlvr.it/Sj532F

Brain 'zips and unzips' information to perform skilled tasks

The human brain prepares skilled movements such as playing the piano, competing in athletics, or dancing by 'zipping and unzipping' information about the timing and order of movements ahead of the action being performed, a new study reveals. http://dlvr.it/Sj4HqS

Sparse, small, but diverse neural connections help make perception reliable, efficient

First detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages 'wisdom of the crowd' to process sensory information. http://dlvr.it/ShsrM1

Learning with all your senses: Multimodal enrichment as the optimal learning strategy of the future

Neuroscientists have compiled extensive interdisciplinary findings from neuroscience, psychology, computer modelling and education on the topic of 'learning' in a recent review article. The results of the interdisciplinary review reveal the mechanisms the brain uses to achieve improved learning outcome by combining multiple senses or movements in learning. This kind of learning outcome applies to a wide variety of domains, such as letter and vocabulary acquisition, reading, mathematics, music, and spatial orientation. http://dlvr.it/Shpz0L

Non-invasive neurotechnology reduces symptoms of insomnia and improves autonomic nervous system function

A new study shows significant improvements in not only sleep quality, but also in improved autonomic nervous system function using a closed-loop, acoustic stimulation neurotechnology. http://dlvr.it/Shm4G3