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Eylül, 2023 tarihine ait yayınlar gösteriliyor

Brain signals for good memory performance revealed

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People differ significantly in their memory performance. Researchers have now discovered that certain brain signals are related to these differences. http://dlvr.it/Swbk5P

Marker for brain inflammation finally decoded

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Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases. A team investigated a marker protein targeted by medical imaging to visualize cerebral inflammation, but whose interpretation was still uncertain. The team reveals that a large quantity of this protein goes hand in hand with a large quantity of inflammatory cells, but its presence is not a sign of their overactivation. These results pave the way for optimal observation of neuroinflammatory processes and a re-reading of previous studies on the subject. http://dlvr.it/SwbVk2

A promising drug candidate for ALS -- prolongs lifespan and eases symptoms in rats and mice

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A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates disease symptoms in rats and mice in animal studies. http://dlvr.it/SwZTfG

Molecular mechanism of psychological loss

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Psychological loss can occur when someone loses a job, loses a sense of control or safety or when a spouse dies. Such loss, which erodes well-being and negatively impacts quality of life, may be a common experience but little is known about the molecular process in the brain that occurs because of loss. New research from the University of Cincinnati explores those mechanisms through a process known as enrichment removal (ER). The study highlights an area of the brain that plays a key role in psychological loss and identifies new molecular targets that may alleviate its impact. http://dlvr.it/SwZTZd

Scientists find new evidence to explain how we pay attention

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A team of researchers has uncovered new clues about how chemicals released by brain cells regulate our attention span. http://dlvr.it/SwVzb0

Why are the brain's nerve cells organized into modules?

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Scientists have revealed that the outer part of our brain (the cortex) is skilled at managing all the info it gets from the outside world thanks to special groups of nerve connections called modules, which work together but also independently. http://dlvr.it/SwTxnG

Exposure to plasticizers in pregnancy associated with smaller volumetric measures in the brain and lower IQ in children

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A study with 775 mother-child pairs in Rotterdam (The Netherlands) finds an association with maternal exposure to certain plasticizers (phthalates) and smaller volumetric measures in the brain of children as well as lower IQ at age 14 http://dlvr.it/SwSFHH

Researchers 'bioprint' living brain cell networks in the lab

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Researchers have successfully used 'bioinks' containing living nerve cells (neurons) to print 3D nerve networks that can grow in the laboratory and transmit and respond to nerve signals. http://dlvr.it/SwQC53

New blood marker can identify Parkinsonian diseases

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Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group is discovering. 'We have observed that an enzyme in cerebrospinal fluid and in blood is a useful marker for identifying all types of Parkinson's-related diseases with high accuracy,' says the study leader. http://dlvr.it/SwPW0l

Revolutionizing brain monitoring and stimulation with thin-film neural electrodes

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Flexible thin-film electrodes placed directly on brain tissue show promise for the diagnosis and treatment of epilepsy. Thanks to an innovative yet straightforward design, these durable electrodes accurately match the mechanical properties of brain tissue, leading to better performance during electrocorticography recordings and targeted neural stimulation. http://dlvr.it/Sw99c8

All work and no play will really make a dull life

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Prioritizing career goals over fun and freedom doesn't make your life better, researchers have found. The study across three countries discovered people who prioritized achievement over enjoyment were less happy on the next day. http://dlvr.it/Sw6zjL

New evidence indicates patients recall death experiences after cardiac arrest

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Up to an hour after their hearts had stopped, some patients revived by cardiopulmonary resuscitation (CPR) had clear memories afterward of experiencing death and had brain patterns while unconscious linked to thought and memory, report investigators. http://dlvr.it/Sw6mzL

Potential new approach to PTSD treatment

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A research study has found that cerebellar inhibitory interneurons are essential for fear memory, a type of emotional memory formation. Inhibitory interneurons within the cerebellar circuitry act as gatekeepers and control the output of the cerebellar cortex. The formation of fear memory requires the activity of these interneurons. The findings may lead to a novel treatment approach for post-traumatic stress disorder. http://dlvr.it/Sw43HJ

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

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New data gives more evidence to the possibility that developing a pathobiome in the brain could cause some forms of Alzheimer's and related dementias. http://dlvr.it/Sw3Vjq

Targeted ultrasound can change brain functions for up to an hour after intervention

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Neuroscientists have explored the impacts of an emerging technique called transcranial ultrasound stimulation (TUS), and showed targeted treatments using it can induce significant changes in GABA (gamma-aminobutyric acid) concentration within the brain's posterior cingulate cortex in the hour following ultrasound treatment. They believe the study could pave the way towards treatment of conditions such as depression, addiction, or anxiety. http://dlvr.it/Sw12mn

New insights into the development of Parkinson's disease in the brain

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Researchers have identified a new pathological mechanism for a familial type of Parkinson's disease caused by a mutation in the CHCHD2 gene. Mutant CHCHD2 protein is mislocalized in cells and leads to alpha-synuclein protein aggregates via interactions with another protein, known as Csnk1e/d. These findings indicate that Csnk1e/d inhibition may slow or halt Parkinson's disease development in patients with CHCHD2 mutations, providing new hope for affected families. http://dlvr.it/SvyhFD

Blood-brain barrier governs ant behavior by altering hormone levels

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In many animals, including ants, the blood-brain barrier (BBB) ensures normal brain function by controlling the movement of various substances in and out of the brain. Now, researchers have made the unexpected discovery that the BBB in carpenter ants plays an active role in controlling behavior that's essential to the function of entire ant colonies. The key is production in the BBB of a particular hormone-degrading enzyme. http://dlvr.it/SvpgMc

A secret passage for mutant protein to invade the brain

In many neurodegenerative disorders, abnormal proteins progressively aggregate and propagate in the brain. But what comes first, aggregation or propagation? Researchers from Japan share some new insights about the mechanism involved in Parkinson's disease. http://dlvr.it/SvndkP

Concussions early in life tied to late life cognitive decline

A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI). http://dlvr.it/SvlD3y

Breakthrough study reveals new insights into GABA, the brain's key signaling molecule

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Scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers have delved into how GABA's levels in the brain are regulated and its broader impacts on cognitive function. http://dlvr.it/SvkRpz

New cause of Alzheimer's, vascular dementia

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Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis -- caused by a buildup of iron in cells -- destroys microglia cells in cases of Alzheimer's and vascular dementia. http://dlvr.it/SvjDkv

Active children are more resilient

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The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise. http://dlvr.it/Svgk2q

Electrical noise stimulation applied to the brain could be key to boosting math learning

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Exciting a brain region using electrical noise stimulation can help improve mathematical learning in those who struggle with the subject, according to a new study. http://dlvr.it/Svckrf

Study could help explain why certain brain tumors don't respond well to immunotherapy

A study sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not. http://dlvr.it/SvW0Df

A new breakthrough in obesity research may allow you to lose fat while eating all you want

This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers have discovered new insights into the regulation of fat metabolism. The focus of their study lies within the star-shaped non-neuronal cells in the brain, known as 'astrocytes'. Furthermore, the group announced successful animal experiments using the newly developed drug 'KDS2010', which allowed the mice to lose weigh without dietary restrictions. http://dlvr.it/SvT4Rq