Kayıtlar

Haziran, 2024 tarihine ait yayınlar gösteriliyor

Resiliency shaped by activity in the gut microbiome and brain

Resim
A new study has found that resilient people exhibit neural activity in the brain regions associated with improved cognition and regulating of emotions, and were more mindful and better at describing their feelings. http://dlvr.it/T8cBnk

Research finds causal evidence tying cerebral small-vessel disease to Alzheimer's, dementia

Resim
While previous studies suggested an association of the most common cerebral small-vessel disease with dementia risk, new research provides evidence of causal link, identifying it as a major vascular factor. http://dlvr.it/T8c15J

Unlocking the entrepreneurial brain: New perspectives on cognitive flexibility

Resim
Pioneering research highlights the importance of combining neuroscience with traditional entrepreneurial studies to gain a comprehensive understanding of what makes successful entrepreneurs distinct at a neurological level. http://dlvr.it/T8c0xp

Removal of ovaries before menopause associated with reduced white matter in brain

Resim
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life, a new study suggests. White matter refers to the nerve fibers that connect neurons in different areas of the brain. http://dlvr.it/T8YpSJ

Shining light on mental health in space science community

Resim
The severity of anxiety and depressive symptoms in the planetary science community is greater than in the general U.S. population, according to a new study. http://dlvr.it/T8WFKW

'Time cells' in the brain are critical for complex learning, study shows

Resim
They're more than a simple clock, and understanding these cells' activity could ultimately aid in early detection of neurodegenerative diseases. http://dlvr.it/T8W2bY

New technology allows researchers to precisely, flexibly modulate brain

Resim
Researchers have developed a noninvasive technology combining a holographic acoustic device with genetic engineering that allows them to precisely target affected neurons in the brain, creating the potential to precisely modulate selected cell types in multiple diseased brain regions. http://dlvr.it/T8Sn2Y

New study reveals urgent need for region-specific models to improve brain health in diverse settings

Resim
A pioneering study has unveiled significant heterogeneity in the risk factors affecting healthy aging in Latin America and emphasized the limitations of current models of brain health, which are primarily based on data from high-income countries. http://dlvr.it/T8SJ5P

Breakthrough approach enables bidirectional BCI functionality

Resim
Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects. This work opens up a new avenue to significantly enhance not only the signal quality, but also, overall nonivasive BCI performance by stimulating targeted neural circuits. http://dlvr.it/T8RY7b

A new approach to neuroimaging analysis

Resim
A new method for neuroimaging analysis is shown to work with small groups of participants, opening the door for many studies that don't have access to massive sets of brain images. http://dlvr.it/T8RXt3

Dopamine linked to mentalizing abilities

Resim
A link between the neurotransmitter dopamine and the mentalizing abilities of healthy people has been identified. http://dlvr.it/T8Q3kJ

New metric for blood circulation in brain to better understand dementia

Resim
Researchers have developed a new metric from measured blood circulation in our brain. This metric has implications for brain conditions, including Alzheimer's disease and other forms of dementia. http://dlvr.it/T8PVsg

New insights into the brain regions involved in paranoia

Resim
The capacity to adjust beliefs about one's actions and their consequences in a constantly changing environment is a defining characteristic of advanced cognition. Disruptions to this ability, however, can negatively affect cognition and behavior, leading to such states of mind as paranoia, or the belief that others intend to harm us. In a new study, scientists uncover how one specific region of the brain might causally provoke these feelings of paranoia. Their novel approach -- which involved aligning data collected from monkeys with human data -- also offers a new cross-species framework through which scientists might better understand human cognition through the study of other species. http://dlvr.it/T8H8sl

Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution

Resim
A suite of three innovations enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution. To demonstrate the advance, researchers compared a brain region in an Alzheimer's and a control sample. http://dlvr.it/T8Fb5W

Fruit fly brain shows how simple commands turn into complex behaviors

Resim
Researchers have discovered how networks of neurons in fruit flies transform simple brain signals into coordinated actions. This sheds light on the neural mechanisms underlying complex behaviors for potential application in robotics. http://dlvr.it/T8FZq8

Are mixed emotions real? New research says yes

Resim
Neuroscientists found that brains display distinct neural activity when experiencing emotions such as bitter-sweetness. The advance could help solve a longstanding scientific debate: whether 'mixed emotions' arise from unique activity in the brain, or if we're just flip-flopping back and forth between positive and negative feelings. http://dlvr.it/T8FM2z

Promising gene therapy for FOXG1 syndrome

Resim
A viral gene therapy has reversed some brain abnormalities in infant mice with FOXG1 syndrome, a significant step toward one day treating children with this severe neurodevelopmental disorder. http://dlvr.it/T8FLrv

Exposure to heat and cold in early life may affect development of white matter in the brain

Resim
Brain scans of more than 2,000 preadolescents suggests that early life exposure to heat and cold may have lasting effects on the microstructure of white matter in the brain, especially when living in poorer neighborhoods. The study highlights the vulnerability of fetuses and children to extreme temperatures. http://dlvr.it/T8CJ9F

Just thinking about a location activates mental maps in the brain

Resim
Researchers found that mental representations known as cognitive maps, located in the hippocampus and entorhinal cortex, are activated when the brain performs mental simulations of a navigational route. http://dlvr.it/T8Bsy0

New study reveals links between social anxiety, depression and suicidal thoughts in adolescents

Resim
A longitudinal study using a big dataset of 2,400 young people recruited from the UK found that social anxiety symptoms (measured at the outset) were significantly associated with more suicidal thoughts and other depressive symptoms two years later. The findings highlight the importance of early identification and treatment of social anxiety in young people. http://dlvr.it/T89ldt

How the brain is affected by Huntington's Disease

Resim
The genetic disease Huntington's not only affects nerve cells in the brain but also has widespread effects on microscopic blood vessels according to research. These changes to the vasculature were also observed in the pre-symptomatic stages of the disease, demonstrating the potential for this research for predicting brain health and evaluating the beneficial effects of lifestyle changes or treatments. Huntington's disease is an inherited genetic condition leading to dementia, with a progressive decline in a person's movement, memory, and cognition. There is currently no cure. http://dlvr.it/T88LQT

Brain's structure hangs in 'a delicate balance'

Resim
Researchers examined anatomy of neurons from humans, mice and fruit flies. They discovered that the cellular structure of the brain is at a critical point, poised between two phases. New insights could help design computational models of the brain's complexity. http://dlvr.it/T87D4d

Multicenter clinical study supports safety of deep general anesthesia

Resim
New research supports earlier findings that indicate that anesthesia is no more hazardous for the brain at higher doses than at lower doses. http://dlvr.it/T86D2h

Women's mental agility is better when they're on their period, study finds

Resim
Participants reacted quicker and made fewer errors during menstruation, despite believing their performance would be worse, according to new research. http://dlvr.it/T86Cj8

Protocol for creating 'wired miniature brains'

Resim
Researchers have developed -- and shared -- a process for creating brain cortical organoids -- essentially miniature artificial brains with functioning neural networks. http://dlvr.it/T860gg

Study identifies potential pathway to reducing breast cancer brain metastases

Resim
A study has identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. http://dlvr.it/T83j8W

Age and sex-related changes leave female flies vulnerable to delayed harm from head injury

Resim
A research team using a fruit fly model has discovered that even very mild, non-lethal head injuries early in life can lead to neurodegenerative conditions later in life upon aging. http://dlvr.it/T83j2F

What's going on in our brains when we plan?

Resim
An international team of scientists has uncovered neural mechanisms used in planning. Its results suggest that an interplay between the brain's prefrontal cortex and hippocampus allows us to imagine future outcomes in order to guide our decisions. http://dlvr.it/T7zyJ4

First-of-its-kind test can predict dementia up to nine years before diagnosis

Resim
Researchers have developed a new method for predicting dementia with over 80% accuracy and up to nine years before a diagnosis. The new method provides a more accurate way to predict dementia than memory tests or measurements of brain shrinkage, two commonly used methods for diagnosing dementia. http://dlvr.it/T7zWZQ

Omega-3 therapy prevents birth-related brain injury in newborn rodents

Resim
A novel omega-3 injectable emulsion reduces brain damage in newborn rodents experiencing lack of oxygen at delivery, a major cause of disability in human infants and children. http://dlvr.it/T7yqyK

The body's own lipids affect mental disorders: Can specific inhibitors help?

Resim
A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and inhibition in neural circuits and promoting mental disorders. However, treatment with an enzyme inhibitor that prevents the activation of lipids can restore balance and alleviate symptoms. http://dlvr.it/T7yqgw

Training cognitive control in children does not change brain or behavior

Resim
Training exercises designed to improve cognitive control in children do not make a significant difference to their ability to delay gratification or to their academic achievement, nor do they lead to any brain changes. http://dlvr.it/T7wN5B

Poor quality diet makes our brains sad

Resim
Eating a poor quality diet might lead to brain changes that are associated with depression and anxiety. This is according to a first-of-its-kind study into the brain chemistry and structure, and diet quality of 30 volunteers. http://dlvr.it/T7tqTB

Internet addiction affects the behavior and development of adolescents

Resim
Adolescents with an internet addiction undergo changes in the brain that could lead to additional addictive behavior and tendencies, finds a new study. http://dlvr.it/T7tqLF

Brain waves shape the words we hear

Resim
The timing of our brain waves shapes which words we hear. Researchers used psychophysics, neuroimaging, and computational modeling to test whether neural timing influences perception of more or less frequent speech sounds and words. Neural timing is sensitive to the probability of words vs. sounds in different brain regions, shaping sound and word recognition. http://dlvr.it/T7tq6l

New deep brain stimulation algorithm may help personalize Parkinson's disease treatment

Resim
Deep brain stimulation (DBS) has shown promise as a treatment for some symptoms of Parkinson s disease (PD). However, not all symptoms improve equally well with DBS. A better understanding of how different sites of electrical stimulation impact the wide range of motor symptoms associated with PD could help fine-tune treatment. By studying PD patients at five different centers treated with DBS, investigators created an atlas that mapped four major symptoms of PD onto different regions of the brain. Based on these findings, the team created an algorithm capable of generating personalized, symptom-specific DBS treatment plans, which they preliminarily tested in five patients. http://dlvr.it/T7srvD

New model allows a computer to understand human emotions

Resim
Researchers have developed a model that enables computers to interpret and understand human emotions, utilizing principles of mathematical psychology. In the future, the model can help the computer to adapt its own behavior and guide an irritated or anxious user in different ways. The implications of such technology are profound, offering a glimpse into a future where computers are not merely tools, but empathetic partners in user interaction. http://dlvr.it/T7srWv

Mapping the mind with BARseq

Resim
A team has scaled up the powerful brain-mapping tool BARseq. The technology is now capable of mapping millions of neurons throughout the brain. Identifying how neural connections are wired up over time is key to understanding the brain's perceptual abilities. It may also lead to better treatments for a variety of neurological conditions. http://dlvr.it/T7nCWZ

Study examines prescribing patterns of drug associated with cognitive impairment

Resim
A new study is one of the first explorations of prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy at healthcare facilities predominantly serving diverse populations of low socioeconomic status. The current body of evidence, much of it established and confirmed in studies by scientists, supports the existence of a relationship between long-term use of anticholinergic medications, such as tricyclic antidepressants, and cognitive impairment, including dementia. Research suggests use of anticholinergics in older adult populations increases risk of dementia 30 to 50 percent. http://dlvr.it/T7jWl4