Revealing the neuronal pathways involved in adaptive decision-making in primates

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Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear. In a recent study, researchers from Japan conducted behavioral experiments on monkeys whose OFC pathways could be selectively silenced chemically. Findings demonstrate how these independent pathways are linked to experience-based adaptation and knowledge-based adaptation in primates.


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